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PCOS or polycystic ovarian syndrome is a complex condition that has a direct impact on the ovaries. This condition is considered complex due to the fact that there are some very particular appearances of the ovaries that give the condition its name, but these traits do not have to be present for a woman to be suffering from PCOS. Specifically, PCOS can impact the woman’s ability to become pregnant.

PCOS is a common cause for anovulation, a condition in which a woman’s body does not release eggs at all or on a regular basis causing irregular periods and difficulty conceiving. Polycystic ovarian syndrome is very common, affecting ten percent of all women between the ages of 15 and 50 making them infertile. For the population at large, PCOS affects twenty five percent of all women.

While PCOS makes getting pregnant difficult, there are a number of very good treatment options available. A rather newer treatment option that has been shown to be very effective is metformin. Metformin is a medication that typically has been used to treat and control diabetes. Metformin is effective in treating PCOS on its own, but not 100 percent of the time.

There are times when metformin is used in conjunction with other medications that treat PCOS such as clomid. This combination has been shown to be effective in helping those women that do not respond to metformin alone to ovulate. Should the combination of metformin and clomid not be effective, metformin can also be used in conjunction with letrozole, injectable FSH hormone, and in vitro fertilization.

There are side effects that are worth noting when using metformin to treat PCOS. Twenty five percent of women that use metformin experience some side effects such as: cramping, nausea, diarrhea and abdominal discomfort. While these side effects are not life threatening, they can become severe enough for a woman to stop using metformin.

If metformin is a treatment option for you, your doctor may order some lab work to make sure metformin is safe for you to use. These lab tests can include a fasting blood sugar and insulin levels, LH, FSH, DHEAS, testosterone, 17-OHP, TSH, kidney function and liver function as well as estradiol. These tests are important because some women may be insulin resistant and these tests can help determine that. Women that are insulin resistant should not take metformin.

There is also patient education that needs to be addressed before a woman takes metformin. For example, knowing when to have intercourse is important. Women will need to know the possibility of ovulating; this means regular intercourse is ideal to increase the chances of a woman becoming pregnant. Regular intercourse is defined as intercourse every two to three days. It is also important that the woman keep a menstrual calendar or journal. Keeping track of the days that there is bleeding and the days that she has intercourse.

Typically metformin will be prescribed at the dosage the woman can tolerate. For most women this is going to be a 500 mg tablet taken three times a day, this dose is built up to gradually. The starting dose is 500 mg once a day for the first week, the second week is 500 mg twice a day, and the third week is a 500 mg tablet three times a day. If taking metformin three times a day cannot be tolerated that woman will be kept on the twice daily regimen, noting that the most effective dose is 500 mg three times a day.

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PCOS or polycystic ovarian syndrome is a complex condition that has a direct impact on the ovaries. This condition is considered complex due to the fact that there are some very particular appearances of the ovaries that give the condition its name, but these traits do not have to be present for a woman to be suffering from PCOS. Specifically, PCOS can impact the woman’s ability to become pregnant.

PCOS is a common cause for anovulation, a condition in which a woman’s body does not release eggs at all or on a regular basis causing irregular periods and difficulty conceiving. Polycystic ovarian syndrome is very common, affecting ten percent of all women between the ages of 15 and 50 making them infertile. For the population at large, PCOS affects twenty five percent of all women.

While PCOS makes getting pregnant difficult, there are a number of very good treatment options available. A rather newer treatment option that has been shown to be very effective is metformin. Metformin is a medication that typically has been used to treat and control diabetes. Metformin is effective in treating PCOS on its own, but not 100 percent of the time.

There are times when metformin is used in conjunction with other medications that treat PCOS such as clomid. This combination has been shown to be effective in helping those women that do not respond to metformin alone to ovulate. Should the combination of metformin and clomid not be effective, metformin can also be used in conjunction with letrozole, injectable FSH hormone, and in vitro fertilization.

There are side effects that are worth noting when using metformin to treat PCOS. Twenty five percent of women that use metformin experience some side effects such as: cramping, nausea, diarrhea and abdominal discomfort. While these side effects are not life threatening, they can become severe enough for a woman to stop using metformin.

If metformin is a treatment option for you, your doctor may order some lab work to make sure metformin is safe for you to use. These lab tests can include a fasting blood sugar and insulin levels, LH, FSH, DHEAS, testosterone, 17-OHP, TSH, kidney function and liver function as well as estradiol. These tests are important because some women may be insulin resistant and these tests can help determine that. Women that are insulin resistant should not take metformin.

There is also patient education that needs to be addressed before a woman takes metformin. For example, knowing when to have intercourse is important. Women will need to know the possibility of ovulating; this means regular intercourse is ideal to increase the chances of a woman becoming pregnant. Regular intercourse is defined as intercourse every two to three days. It is also important that the woman keep a menstrual calendar or journal. Keeping track of the days that there is bleeding and the days that she has intercourse.

Typically metformin will be prescribed at the dosage the woman can tolerate. For most women this is going to be a 500 mg tablet taken three times a day, this dose is built up to gradually. The starting dose is 500 mg once a day for the first week, the second week is 500 mg twice a day, and the third week is a 500 mg tablet three times a day. If taking metformin three times a day cannot be tolerated that woman will be kept on the twice daily regimen, noting that the most effective dose is 500 mg three times a day.

If you do a search for metformin and weight loss on the internet, you’ll find a slew of forums and websites talking about this particular drug and how it can be used to melt fat from your body. You’ll also find many forum posts of individuals who state that they’ve been using it for weeks, but they haven’t even lost a pound.

Can you lose weight with metformin? The truth is that it may help you lose weight, but it must be part of a complete program. Let’s go into more detail.

What is Metformin?

Metformin is a drug (under the trade name Glucophage, but there are also generic versions) that is used to treat type II diabetes. Initially it was never intended to be a diet drug. But interestingly enough, the qualities of this drug that help with diabetes might aid you in your efforts to lose weight.

How Does Metformin Work?

There is a process inside your body, in your liver, that turns carbohydrates into blood sugar (or glucose). When you eat too many grams of carbohydrates, particularly simple or refined carbohydrates (e. g. processed flour, sugar, etc.), the liver produces a high level of glucose. When your glucose levels rise above a certain point, your body releases insulin in order to counteract the spike of blood sugar.

The insulin causes the body to “suck up” the glucose and store it in fat cells throughout your body. This is what causes a person to gain weight and even become obese. And this process being repeated continually over many years is what causes the body to become insulin resistant.

That’s where metformin comes in. In patients with type II diabetes, whose bodies produce on average three times the normal glucose, the medication reduces the production of glucose by more than a third. Metformin reduces the amount of glucose produced by the liver, thus reducing the needed insulin to stabilize the blood sugar.

It may not have as dramatic effect in individuals who don’t have type II diabetes, but it still reduces the amount of glucose produced by the liver, even in pre-diabetic individuals. This means that (whether you have diabetes or not) if you’re overweight, metformin may help you lose weight and reduce your risk of diabetes.

Does It Really Work for Weight Loss?

Keep in mind that metformin isn’t a miracle diet pill. The link between metformin and weight loss consists of more than simply taking a “magical pill”. Also, much more research needs to be done regarding metformin and weight loss. However, there are anecdotal instances (people’s own experiences) available to read if you care to do some research.

Most who assert that this drug has helped them lose weight attest to the fact that they used metformin as a part of their weight loss program. One caution to be aware of is that metformin in combination with a very restrictive diet may cause hypoglycemia (low blood sugar). It is certainly recommended that a competent doctor is consulted before making metformin a part of your weight loss program.

Based on simple logic concerning how this drug affects the human body, there may indeed be a very beneficial link between metformin and weight loss.

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Article Source:
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PCOS or polycystic ovarian syndrome is a complex condition that has a direct impact on the ovaries. This condition is considered complex due to the fact that there are some very particular appearances of the ovaries that give the condition its name, but these traits do not have to be present for a woman to be suffering from PCOS. Specifically, PCOS can impact the woman’s ability to become pregnant.

PCOS is a common cause for anovulation, a condition in which a woman’s body does not release eggs at all or on a regular basis causing irregular periods and difficulty conceiving. Polycystic ovarian syndrome is very common, affecting ten percent of all women between the ages of 15 and 50 making them infertile. For the population at large, PCOS affects twenty five percent of all women.

While PCOS makes getting pregnant difficult, there are a number of very good treatment options available. A rather newer treatment option that has been shown to be very effective is metformin. Metformin is a medication that typically has been used to treat and control diabetes. Metformin is effective in treating PCOS on its own, but not 100 percent of the time.

There are times when metformin is used in conjunction with other medications that treat PCOS such as clomid. This combination has been shown to be effective in helping those women that do not respond to metformin alone to ovulate. Should the combination of metformin and clomid not be effective, metformin can also be used in conjunction with letrozole, injectable FSH hormone, and in vitro fertilization.

There are side effects that are worth noting when using metformin to treat PCOS. Twenty five percent of women that use metformin experience some side effects such as: cramping, nausea, diarrhea and abdominal discomfort. While these side effects are not life threatening, they can become severe enough for a woman to stop using metformin.

If metformin is a treatment option for you, your doctor may order some lab work to make sure metformin is safe for you to use. These lab tests can include a fasting blood sugar and insulin levels, LH, FSH, DHEAS, testosterone, 17-OHP, TSH, kidney function and liver function as well as estradiol. These tests are important because some women may be insulin resistant and these tests can help determine that. Women that are insulin resistant should not take metformin.

There is also patient education that needs to be addressed before a woman takes metformin. For example, knowing when to have intercourse is important. Women will need to know the possibility of ovulating; this means regular intercourse is ideal to increase the chances of a woman becoming pregnant. Regular intercourse is defined as intercourse every two to three days. It is also important that the woman keep a menstrual calendar or journal. Keeping track of the days that there is bleeding and the days that she has intercourse.

Typically metformin will be prescribed at the dosage the woman can tolerate. For most women this is going to be a 500 mg tablet taken three times a day, this dose is built up to gradually. The starting dose is 500 mg once a day for the first week, the second week is 500 mg twice a day, and the third week is a 500 mg tablet three times a day. If taking metformin three times a day cannot be tolerated that woman will be kept on the twice daily regimen, noting that the most effective dose is 500 mg three times a day.

If you do a search for metformin and weight loss on the internet, you’ll find a slew of forums and websites talking about this particular drug and how it can be used to melt fat from your body. You’ll also find many forum posts of individuals who state that they’ve been using it for weeks, but they haven’t even lost a pound.

Can you lose weight with metformin? The truth is that it may help you lose weight, but it must be part of a complete program. Let’s go into more detail.

What is Metformin?

Metformin is a drug (under the trade name Glucophage, but there are also generic versions) that is used to treat type II diabetes. Initially it was never intended to be a diet drug. But interestingly enough, the qualities of this drug that help with diabetes might aid you in your efforts to lose weight.

How Does Metformin Work?

There is a process inside your body, in your liver, that turns carbohydrates into blood sugar (or glucose). When you eat too many grams of carbohydrates, particularly simple or refined carbohydrates (e. g. processed flour, sugar, etc.), the liver produces a high level of glucose. When your glucose levels rise above a certain point, your body releases insulin in order to counteract the spike of blood sugar.

The insulin causes the body to “suck up” the glucose and store it in fat cells throughout your body. This is what causes a person to gain weight and even become obese. And this process being repeated continually over many years is what causes the body to become insulin resistant.

That’s where metformin comes in. In patients with type II diabetes, whose bodies produce on average three times the normal glucose, the medication reduces the production of glucose by more than a third. Metformin reduces the amount of glucose produced by the liver, thus reducing the needed insulin to stabilize the blood sugar.

It may not have as dramatic effect in individuals who don’t have type II diabetes, but it still reduces the amount of glucose produced by the liver, even in pre-diabetic individuals. This means that (whether you have diabetes or not) if you’re overweight, metformin may help you lose weight and reduce your risk of diabetes.

Does It Really Work for Weight Loss?

Keep in mind that metformin isn’t a miracle diet pill. The link between metformin and weight loss consists of more than simply taking a “magical pill”. Also, much more research needs to be done regarding metformin and weight loss. However, there are anecdotal instances (people’s own experiences) available to read if you care to do some research.

Most who assert that this drug has helped them lose weight attest to the fact that they used metformin as a part of their weight loss program. One caution to be aware of is that metformin in combination with a very restrictive diet may cause hypoglycemia (low blood sugar). It is certainly recommended that a competent doctor is consulted before making metformin a part of your weight loss program.

Based on simple logic concerning how this drug affects the human body, there may indeed be a very beneficial link between metformin and weight loss.

Just like any medication, Metformin will produce fall out. But not everyone who is on Metformin therapy experiences the fall-out of the drug. As a matter of fact, some people can just tolerate using it. When effects are experienced, they are usually not severe and they may either be treated easily by your physician, or treatment will not be necessary at all.

The common Metformin have been established through series of clinical trials on people. During the clinical trials, the effects experienced by one group who is on Metformin, will be compared to the bad effects experienced by another group who is not taking the drug. Studies show that diarrhea, nausea and vomiting, gas, indigestion, abdominal discomfort, weakness, and headache, are the usual Metformin. In general, people who are taking the extended formulation of Metformin, will experience fewer of these effects.

When there are minor fall outs produced, there are also severe fall effects which may result from drug overdosing, or any health condition that can affect the efficacy of the therapy. Should these severe fall outs occur, notify your physician immediately. The following are severe side effects that may require immediate medical attention. These include, but will not only limit to:

• Lactic Acidosis – symptoms include easy fatigability, muscular pain, labored breathing, abdominal pain, dizziness, cold and clammy skin, and either an irregular or slow heartbeat

• Increase in blood sugar levels which produce symptoms such as increased thirst, increased urination, increased food cravings, blurring of vision, shortness of breath, fatigue, or nausea and vomiting

• Decrease in blood sugar levels which produce symptoms like sweating, extreme hunger, dizziness, irritability or changes in behavior, confusion, shakiness, cold sweats, loss of coordination, or seizures

• Allergic reactions which include appearance of skin rash, labored breathing, itching, or unexplained swelling and

• Chest pain

There are also other Metformin fall effects which are not commonly experienced and in clinical trials, only 1-5% of the subjects experienced the fall outs. These include taste changes, flu-like symptoms such as weakness, muscle pain, and chills, flushing, or palpitations.

You could either experience some or none of the fall effects mentioned above. Your physician will not be able to predict the side effects you are going to feel especially if you have not tried Metformin. That is why it is crucial to inform the physician of any unusual fall outs that you may have experienced while on Metformin therapy. Let your physician know, so he could do something to fix the problem immediately.

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Article Source:
http://EzineArticles.com/expert/Ivan_Gordon/645922

PCOS or polycystic ovarian syndrome is a complex condition that has a direct impact on the ovaries. This condition is considered complex due to the fact that there are some very particular appearances of the ovaries that give the condition its name, but these traits do not have to be present for a woman to be suffering from PCOS. Specifically, PCOS can impact the woman’s ability to become pregnant.

PCOS is a common cause for anovulation, a condition in which a woman’s body does not release eggs at all or on a regular basis causing irregular periods and difficulty conceiving. Polycystic ovarian syndrome is very common, affecting ten percent of all women between the ages of 15 and 50 making them infertile. For the population at large, PCOS affects twenty five percent of all women.

While PCOS makes getting pregnant difficult, there are a number of very good treatment options available. A rather newer treatment option that has been shown to be very effective is metformin. Metformin is a medication that typically has been used to treat and control diabetes. Metformin is effective in treating PCOS on its own, but not 100 percent of the time.

There are times when metformin is used in conjunction with other medications that treat PCOS such as clomid. This combination has been shown to be effective in helping those women that do not respond to metformin alone to ovulate. Should the combination of metformin and clomid not be effective, metformin can also be used in conjunction with letrozole, injectable FSH hormone, and in vitro fertilization.

There are side effects that are worth noting when using metformin to treat PCOS. Twenty five percent of women that use metformin experience some side effects such as: cramping, nausea, diarrhea and abdominal discomfort. While these side effects are not life threatening, they can become severe enough for a woman to stop using metformin.

If metformin is a treatment option for you, your doctor may order some lab work to make sure metformin is safe for you to use. These lab tests can include a fasting blood sugar and insulin levels, LH, FSH, DHEAS, testosterone, 17-OHP, TSH, kidney function and liver function as well as estradiol. These tests are important because some women may be insulin resistant and these tests can help determine that. Women that are insulin resistant should not take metformin.

There is also patient education that needs to be addressed before a woman takes metformin. For example, knowing when to have intercourse is important. Women will need to know the possibility of ovulating; this means regular intercourse is ideal to increase the chances of a woman becoming pregnant. Regular intercourse is defined as intercourse every two to three days. It is also important that the woman keep a menstrual calendar or journal. Keeping track of the days that there is bleeding and the days that she has intercourse.

Typically metformin will be prescribed at the dosage the woman can tolerate. For most women this is going to be a 500 mg tablet taken three times a day, this dose is built up to gradually. The starting dose is 500 mg once a day for the first week, the second week is 500 mg twice a day, and the third week is a 500 mg tablet three times a day. If taking metformin three times a day cannot be tolerated that woman will be kept on the twice daily regimen, noting that the most effective dose is 500 mg three times a day.

If you do a search for metformin and weight loss on the internet, you’ll find a slew of forums and websites talking about this particular drug and how it can be used to melt fat from your body. You’ll also find many forum posts of individuals who state that they’ve been using it for weeks, but they haven’t even lost a pound.

Can you lose weight with metformin? The truth is that it may help you lose weight, but it must be part of a complete program. Let’s go into more detail.

What is Metformin?

Metformin is a drug (under the trade name Glucophage, but there are also generic versions) that is used to treat type II diabetes. Initially it was never intended to be a diet drug. But interestingly enough, the qualities of this drug that help with diabetes might aid you in your efforts to lose weight.

How Does Metformin Work?

There is a process inside your body, in your liver, that turns carbohydrates into blood sugar (or glucose). When you eat too many grams of carbohydrates, particularly simple or refined carbohydrates (e. g. processed flour, sugar, etc.), the liver produces a high level of glucose. When your glucose levels rise above a certain point, your body releases insulin in order to counteract the spike of blood sugar.

The insulin causes the body to “suck up” the glucose and store it in fat cells throughout your body. This is what causes a person to gain weight and even become obese. And this process being repeated continually over many years is what causes the body to become insulin resistant.

That’s where metformin comes in. In patients with type II diabetes, whose bodies produce on average three times the normal glucose, the medication reduces the production of glucose by more than a third. Metformin reduces the amount of glucose produced by the liver, thus reducing the needed insulin to stabilize the blood sugar.

It may not have as dramatic effect in individuals who don’t have type II diabetes, but it still reduces the amount of glucose produced by the liver, even in pre-diabetic individuals. This means that (whether you have diabetes or not) if you’re overweight, metformin may help you lose weight and reduce your risk of diabetes.

Does It Really Work for Weight Loss?

Keep in mind that metformin isn’t a miracle diet pill. The link between metformin and weight loss consists of more than simply taking a “magical pill”. Also, much more research needs to be done regarding metformin and weight loss. However, there are anecdotal instances (people’s own experiences) available to read if you care to do some research.

Most who assert that this drug has helped them lose weight attest to the fact that they used metformin as a part of their weight loss program. One caution to be aware of is that metformin in combination with a very restrictive diet may cause hypoglycemia (low blood sugar). It is certainly recommended that a competent doctor is consulted before making metformin a part of your weight loss program.

Based on simple logic concerning how this drug affects the human body, there may indeed be a very beneficial link between metformin and weight loss.

Just like any medication, Metformin will produce fall out. But not everyone who is on Metformin therapy experiences the fall-out of the drug. As a matter of fact, some people can just tolerate using it. When effects are experienced, they are usually not severe and they may either be treated easily by your physician, or treatment will not be necessary at all.

The common Metformin have been established through series of clinical trials on people. During the clinical trials, the effects experienced by one group who is on Metformin, will be compared to the bad effects experienced by another group who is not taking the drug. Studies show that diarrhea, nausea and vomiting, gas, indigestion, abdominal discomfort, weakness, and headache, are the usual Metformin. In general, people who are taking the extended formulation of Metformin, will experience fewer of these effects.

When there are minor fall outs produced, there are also severe fall effects which may result from drug overdosing, or any health condition that can affect the efficacy of the therapy. Should these severe fall outs occur, notify your physician immediately. The following are severe side effects that may require immediate medical attention. These include, but will not only limit to:

• Lactic Acidosis – symptoms include easy fatigability, muscular pain, labored breathing, abdominal pain, dizziness, cold and clammy skin, and either an irregular or slow heartbeat

• Increase in blood sugar levels which produce symptoms such as increased thirst, increased urination, increased food cravings, blurring of vision, shortness of breath, fatigue, or nausea and vomiting

• Decrease in blood sugar levels which produce symptoms like sweating, extreme hunger, dizziness, irritability or changes in behavior, confusion, shakiness, cold sweats, loss of coordination, or seizures

• Allergic reactions which include appearance of skin rash, labored breathing, itching, or unexplained swelling and

• Chest pain

There are also other Metformin fall effects which are not commonly experienced and in clinical trials, only 1-5% of the subjects experienced the fall outs. These include taste changes, flu-like symptoms such as weakness, muscle pain, and chills, flushing, or palpitations.

You could either experience some or none of the fall effects mentioned above. Your physician will not be able to predict the side effects you are going to feel especially if you have not tried Metformin. That is why it is crucial to inform the physician of any unusual fall outs that you may have experienced while on Metformin therapy. Let your physician know, so he could do something to fix the problem immediately.

Some elements are activated by the Metformin and those are identified and also isolated. Biguanides is a kind of drugs and it is contains the compounds. Two connected rings of guanidine made Metformin. This is used for some long term treatment for some disease such as diabetes and the way is not completely known to the doctors. How the medicine works and very recently some actions are detected by the scientists. Metformin is very effective on the metabolism of the glucose in some conditions. So, the insulin compassion in some tissues such as the liver or the muscles is increased for this compound.

Some additional advantages of the Metformin is it reduces the gluconeogenesis or glucose synthesis from liver of noncarbohydrate source. The level of the glucose is reduced by the help of the Metforming. But one thing is that the Metformin is some kind of agent of euglycaemic and the level of glucose of the blood remains same without falling the danger level and for this reason the Hypoglycaemic problems can’t be occurred. The circulation of the fatty acids also remains lower and there are also some advantages over the metabolism of the lipid. VLDL is also decrease and the diseases of cardiovascular such as the fatty acids circulation.

Insulin is one of the reasons to be overweighed. As this type of fat is gathered in the abdomen and when people eat the level of the sugar is also increased. The rate of release of the insulin in pancreas is increased when the level of the sugar increased. This insulin is the cause of your fatness and working for the stimulation in the brain to raise hunger. As a result the liver lost its control and the fat cells of the abdomen fill with the fat. To avoid this be concern about food selection and avoid fat foods and can take some medicine that can control the sugar level in the blood.

Any types of junk foods from bakery and foods like pastas, flour made foods and all kinds of foods that rich with sugar should be removed from your food list. Potatoes and different types of foods should be added in your daily meal.

Glucophage is one element that is in the Metformin and it can reduce the level of the sugar. The body has no need to create much insulin which is the reason of the hungriness and also the sugar never converted to fat by the liver. Some other advantages of Metformin has caused such as the lost of the weight of the body and the safety from the diabetes. When the lactic acid is increased in the blood and it become acidic then the Metformin is useless. The glucopahge can help in this situation. Many researches show that the glucophage can control the lactic acid and keep blood safe from being acidic.

Metformin can help to control the insulin level and it is a good treatment against the diabetes. It will help to maintain the glucose level and also help to keep control in the resistance of the insulin. The chance of heart attack also is reduced by the Metformin.

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http://EzineArticles.com/expert/Eric_Spinosus/494810

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